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  1. A protein that can melt tumors discovered at Vanderbilt

    ... noodle-like protein performs important functions in normal human development, and it often becomes reactivated in the deadliest and most ...

    sommers - 02/01/2021 - 10:02am

  2. VUMC Licensee Evotec Starts Clinical Development of Chikungunya Antibody

    ... double-blind, single centre, single dose escalation study to evaluate the safety, pharmacokinetics, and immunogenicity of EVT894 vs ... chikungunya infection or disease.   EVT894 is a fully human monoclonal antibody that targets a viral protein and has shown potent ...

    sommers - 01/29/2021 - 8:45am

  3. New tool may speed antibody, vaccine research

    ... lineage of broadly neutralizing antibodies against the human immunodeficiency virus (HIV), which causes AIDS. “The method really ... unable to ask,” he said. “We’re starting to study new targets within the HIV infection and vaccination field, but we’re ...

    sommers - 12/16/2019 - 3:04pm

  4. Monoclonal antibody “cocktail” blocks COVID-19 variants: study

    ... protein other than the highly mutable E484K residue. The study indicated substantially reduced neutralization of variants viruses ... methods  for discovering highly potent antiviral human monoclonal antibodies and validating their ability to protect small ...

    sommers - 03/08/2021 - 8:39am

  5. Vanderbilt-developed obesity treatments will be advanced through collaboration with Soleno Therapeutics

    ... of anesthesiology and pharmacology and director of ion channel pharmacology at the WCNDD. The Vanderbilt–Soleno partnership, ... that leads to obesity. “K ATP  channels have a long history of being useful therapeutic targets for treating type 2 diabetes, ... translating academic research into meaningful outcomes for human health.” ...

    sommers - 02/25/2021 - 9:56am

  6. VUMC joins international effort to speed vaccine development

    ... methods to quickly isolate and generate large quantities of human monoclonal antibodies from the blood of people who survived outbreaks of ... Orleans, will guide clinical development of first-in-class human immunotherapies against multiple Lassa virus lineages. Alphaviruses ...

    sommers - 06/07/2019 - 9:28am

  7. Tech Connect, Vol. 7, Issue 22: Forum highlights innovative approaches to bolstering biomedical research

    ... Drug Development company to further discussions regarding human behavioral analysis technologies developed by Nilanjan Sarkar in the ... Engineering an exclusive license to human antibodies as therapeutics for infectious disease discovered by James E. ...

    steelmk - 07/21/2017 - 3:39pm

  8. VUMC studies provide key positive results for COVID-19 vaccine in early-stage clinical trial

    ... their name. The spike protein binds to receptors on human cells and enables virus entry. It is required for infection and is the ...

    sommers - 08/19/2020 - 7:50pm

  9. USPTO awards Crowe Lab and Vanderbilt an Honorable Mention in 2018's Patents for Humanity Winners

    ... the outbreak, the Vanderbilt team isolated and characterized human monoclonal antibodies that specifically target Zika virus proteins and ... lines engineered to produce these antibodies. Fortunately, long before Zika made global headlines, Dr. James E. Crowe, Jr., Director of ...

    sommers - 02/21/2019 - 9:51am

  10. VU teams take top two slots, $45K at 36|86 student pitch competition

    ... and uses machine learning, natural language processing and human scribes to turn the audio into medical documentation. Team ...

    sommers - 02/21/2019 - 9:51am