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Protein that protects probiotics from desiccation, leading to improved gut colonization

Probiotic supplements undergo significant water loss before consumption, killing many of their bacteria and rendering them less effective. Vanderbilt researchers have discovered a protein that protects against damage caused by desiccation and shown that this molecular shield can be added to probiotics to help them survive and colonize the gut. This platform technology can be broadly incorporated into new or existing supplements to make them more efficacious and even improve costs and distribution.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Eric Skaar, Erin Green
Therapeutics

An Ergothioneine PET Radioligand for Imaging Oxidative Stress in Alzheimer's Disease

Vanderbilt researchers lead by Professor Wellington Pham, PhD, have developed a novel ergothioneine (ERGO) PET radioligand for imaging oxidative stress in Alzheimer's disease.


Licensing Contact

Masood Machingal

615.343.3548
Therapeutics
Neuroscience/Neurology

Cooling-Responsive Gel for Local Drug Delivery Applications

Vanderbilt researchers have created a cooling-responsive gel implant that meets the need for non-invasive local drug delivery and is simple to activate, requiring only an ice pack for some applications, eliminating complex clinical equipment. This implant is ideal for alternative pain management or delivery of cancer therapeutics.


Licensing Contact

Philip Swaney

615.322.1067

Inventors

Leon Bellan
Therapeutics

Antimicrobial Compounds and Methods of Use Thereof

Vanderbilt researchers, led by Eric Skaar, Ph.D., have identified novel compounds that are antimicrobial. These compounds represent a first in class as they target a new bacterial pathway that has never been targeted as an antimicrobial strategy.


Licensing Contact

Karen Rufus

615.322.4295
Therapeutics