Browse Technologies

Displaying 11 - 20 of 51

Miniature Optical Coherence Tomography Probe for Real-time Monitoring of Surgery

Vanderbilt researchers have designed a forward scanning miniature intraoperative Optical Coherence Tomography (OCT) probe that can be used for diagnostic purposes and real-time monitoring of surgery within small spaces, such as endoscopic surgery, intraocular surgery, and other microsurgery.

Licensing Contact

Taylor Jordan

615.936.7505

Inventors

Karen Joos, Jin-Hui Shen, M. Hutson, John Kozub
Category:
Medical Devices Medical Imaging

Model-based Compression Correction Framework for Ultrasound

Vanderbilt researchers have developed a system that corrects for compressional effects in ultrasound data during soft tissue imaging. The system uses tracking and digitization information to detect the pose of the ultrasound probe during imaging, and then couples this information with a biomechanical model of the tissue to correct compressional effects during intraoperative imaging.

Licensing Contact

Philip Swaney

615.322.1067

Inventors

Michael Miga, Thomas Pheiffer, Dave Smith
Category:
Computer Science & Communications Medical Imaging

NMR Signal Amplification by Reversible Exchange (SABRE) in Water

Vanderbilt researchers have developed a method to perform the Parahydrogen Induced Polarization (PHIP) based method of Signal Amplification by Reversible Exchange (SABRE) in aqueous media. This allows the resulting hyperpolarized molecules to be used for in vivo applications.

Licensing Contact

Chris Harris

615.343.4433

Inventors

Eduard Chekmenev, Boyd Goodson, Milton Truong, Ping He, Quinn Best, Fan Shi, Kirsten Groome, Aaron Coffey, Roman Shchepin
Category:
Medical Imaging

System and Methods for Contact Detection and Localization in Continuum Robots

This technology expands the capabilities of continuum robots with a system and method that enables them to detect instances of contact and to estimate the position of the contact. This framework allows the motion of the robot to be constrained so as to ensure the robot doesn't damage itself, another robot arm, or surrounding environments. Applications for this technology include enhanced safe telemanipulation for multi-arm continuum robots in surgery, micro-assembly in confined spaces, and exploration in unknown environments.

Licensing Contact

Masood Machingal

615.343.3548

Inventors

Nabil Simaan, Andrea Bajo
Category:
Computer Science & Communications Robotics

System and Methods of Using Image-guidance for Placement of Cochlear Stimulator Devices, Drug Carrier Devices, or the Like

Vanderbilt inventors have developed and tested a device (C-in) and method that would shift the current invasive, risky surgical procedure of cochlear implantation to a less invasive outpatient procedure.

Licensing Contact

Taylor Jordan

615.936.7505

Inventors

Robert Labadie, J Michael Fitzpatrick
Category:
Medical Devices Medical Imaging

Two Degrees-of-Freedom, Fluid Power Stepper Actuator Model

Vanderbilt researchers have developed a novel technology for use of a flexible fluidic actuator in MRI-guided surgical systems. This method eliminates the need for moving the patient out of the MRI machine, onto an operating table, and back in order to perform procedures. It is a safe, sterilized, and successful method to simplify MRI-guided surgical procedures.

Licensing Contact

Taylor Jordan

615.936.7505

Inventors

David Comber, Eric Barth, Jonathan Slightam, Vito Gervasi
Category:
Medical Devices Medical Imaging

TagDock: An Efficient Rigid Body Molecular Docking Algorithm For Three Dimensional Models of Oligomeric Biomolecular Complexes With Limited Experimental Restraint Data

TagDock is an efficient rigid body molecular docking algorithm that generates three-dimensional models of oligomeric biomolecular complexes in instances where there is limited experimental restraint data to guide the docking calculations. Through "distance difference analysis" TagDock additionally recommends followup experiments to further discriminate divergent (score-degenerate) clusters of TagDock's initial solution models

Licensing Contact

Masood Machingal

615.343.3548

Inventors

Terry Lybrand, Jarrod Smith, Christopher Moth, Sarah Edwards
Category:
Bioinformatics Computer Science & Communications Research Tools

PIQASO: A rigid phantom for comprehensive end-to-end evaluation of online adaptive radiotherapy systems

There is currently no radiotherapy phantom capable of quantitatively assessing all components of an online adaptive radiotherapy (online ART) system in a comprehensive end-to-end test.Represented here is a novel, rigid phantom that can simultaneously evaluate an online ART system's image acquisition, deformable image registration, contour propagation, plan re-optimization, dose calculation, and beam delivery in a single process that is robust, quantitative, and convenient.

Licensing Contact

Masood Machingal

615.343.3548

Inventors

Adam Yock, Abby Dare, Michael Price
Category:
Diagnostics Medical Devices Medical Imaging

Inexpensive Disposable Hydro-Jet Capsule Robot for Gastric Cancer Screening in Low-Income Countries

Gastric cancer is the second leading cause of cancer death worldwide. While screening programs have had a tremendous impact on reducing mortality, the majority of cases occur in low and middle-income countries (LMIC). Typically, screening for gastric and esophageal cancer is performed using a flexible endoscope; however, endoscopy resources for these settings are traditionally limited. With the development of an inexpensive, disposable system by Vanderbilt researchers, gastroscopy and colonoscopy can be facilitated in areas hampered by a lack of access to the appropriate means.

Licensing Contact

Masood Machingal

615.343.3548

Inventors

Pietro Valdastri, Keith Obstein, Christopher Lyne, Robert Caprara, Will Jones, Alexander Vartanian, Douglas Morgan, Erdem Erdemir, Federico Campisano, Christian Di Natali, Gabriel Scozzarro, Marco Beccani
Category:
Medical Devices Medical Imaging Robotics
Field of Use:
Gastrointestinal

A Method to Obtain Uniform Radio Frequency Fields in the Body for High Field MRI

Researchers at Vanderbilt have created a new approach to produce uniform radio frequency (RF) fields in the body during high field magnetic resonance imaging (MRI). Existing high field MRI machines create non-uniform RF fields that lead to non-uniform sensitivity in the generated images, also referred to as "hot" and "cold" spots. These local variations interfere with the tissue contrast of the images that radiologists depend upon to make accurate diagnoses. By generating uniform RF fields in the body, this technology provides the benefits of high field MRI without the non-uniform RF fields.

Licensing Contact

Chris Harris

615.343.4433

Inventors

Adam Anderson, John Gore
Category:
Medical Imaging